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top articlesphoto to commentEARLY SHEDDING Normally, skin cells mature and drop from the skin’s surface every 28 days. In psonasis, however, skin cells mature every 3 to 4 days. As a result, they pile up on the skins surface and form the visible lesions of psoriasis: patches reddish skin covered with silvery scales. Studies indicate that an abnormal immune response spurs the overproduction of skin cells by activating T cells, white blood cells that normally protect the body against infection. Once activated, the I cells migrate into the skin and release cytokines — chemicals used by the immune system to communicate messages In psoriasis, cytokines induce skin cells to reproduce and mature at an accelerated pace Lesons may appear anywhere but most commonly form on the elbows, knees, scalp, and lower back. There may be itching, burning, or pain, and the affected skin may also cracK and bleed. In many people, psoriasis is marked by cycles of flares and remissions. Flare-ups can be triggered by such things as sunburn, certain medications, a strep infection (sore throat) or emotional stress.

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